Metabolic Fate of Ingested (14C)-Maltitol in Man.

Observations on the fate of ingested cholesterol in man.

The Fate of Ingested Water

Except in some of the lower orders, virtual constancy of the volume of body water is a prerequisite for the normal function and indeed the survival of the organism. In terrestrial animals, particularly, adaptive mechanisms provide for physiological regulation of the amounts of water which leave and enter the body. Although solid foods provide a considerable quantity of pre-formed water to the b...

The metabolic fate of amphetamine in man and other species.

1. The fate of [(14)C]amphetamine in man, rhesus monkey, greyhound, rat, rabbit, mouse and guinea pig has been studied. 2. In three men receiving orally 5mg each (about 0.07mg/kg), about 90% of the (14)C was excreted in the urine in 3-4 days. About 60-65% of the (14)C was excreted in 1 day, 30% as unchanged drug, 21% as total benzoic acid and 3% as 4-hydroxyamphetamine. 3. In two rhesus monkeys...

The physiological disposition and metabolic fate of cortisone in man.

In an earlier paper we described studies on the physiological disposition and metabolic fate of hydrocortisone in man (1). This paper describes similar studies on cortisone. Although contributing very little to the body pool of adrenal cortical steroids, cortisone has been used extensively as a therapeutic agent, and it was therefore of interest to compare its metabolism with that of hydrocorti...

The metabolic fate of C14 labeled pentoses in man.

The role of pentoses in intermediary metabolism has received much attention within the past few years. The phosphate esters of D-ribose, D-ribulose and D-xylulose have been identified as key intermediates in the pentose phosphate pathway of glucose metabolism in both plant and mammalian tissue (1). More recently, another alternate pathway of glucose dissimilation, the uronic acid pathway, has b...